Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles

Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles

Expression of the CTLA-4 gene is absolutely required for immune homeostasis, but aspects of its molecular nature remain undefined. In particular, the characterization of the soluble CTLA-4 (sCTLA-4) protein isoform generated by an alternatively spliced mRNA of CTLA4 lacking transmembrane-encoding ex...

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Bibliographic Details
Main Authors: Esposito, Laura, Hunter, Kara M. D., Clark, Jan, Rainbow, Daniel B., Stevens, Helen, Denesha, Jennifer, Duley, Simon, Dawson, Sarah, Coleman, Gillian, Nutland, Sarah, Bell, Gwynneth L., Moran, Carla, Pekalski, Marcin, Todd, John A., Wicker, Linda S.
Format: Online
Language:English
Published: AAI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082723/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082723/

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