Comparison of K-ras mutations in lung, colorectal and gastric cancer
K-ras is involved in the EGFR pathway that regulates cell survival, motility and proliferation, as well as angiogenesis and metastasis. It is also essential for carcinogenesis. The K-ras mutation status can be used to predict the therapeutic efficacy of targeted drugs such as cetuximab. The aim of t...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
D.A. Spandidos
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081128/ |