Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at night

Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at night

Expression of long interspersed element-1 (L1) is upregulated in many human malignancies. L1 can introduce genomic instability via insertional mutagenesis and DNA double-strand breaks, both of which may promote cancer. Light exposure at night, a recently recognized carcinogen, is associated with an...

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Bibliographic Details
Main Authors: deHaro, Dawn, Kines, Kristine J., Sokolowski, Mark, Dauchy, Robert T., Streva, Vincent A., Hill, Steven M., Hanifin, John P., Brainard, George C., Blask, David E., Belancio, Victoria P.
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081101/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081101/

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