Frequent disruption of the RB pathway in indolent follicular lymphoma suggests a new combination therapy

Frequent disruption of the RB pathway in indolent follicular lymphoma suggests a new combination therapy

CDK4 activation/RB phosphorylation occurs in 50% of indolent but high-risk follicular lymphomas and implies susceptibility to dual CDK4 and BCL2 inhibition.

Bibliographic Details
Main Authors: Oricchio, Elisa, Ciriello, Giovanni, Jiang, Man, Boice, Michael H., Schatz, Jonathan H., Heguy, Adriana, Viale, Agnes, de Stanchina, Elisa, Teruya-Feldstein, Julie, Bouska, Alyssa, McKeithan, Tim, Sander, Chris, Tam, Wayne, Seshan, Venkatraman E., Chan, Wing-Chung, Chaganti, R.S.K., Wendel, Hans-Guido
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076578/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076578/

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