Mapping glucose-mediated gut-to-brain signalling pathways in humans☆
•We have identified two distinct CNS responses to glucose in man.•A CCK1 receptor (CCK1R)-dependent BOLD signal increase in the motor cortex.•A CCK1R-independent BOLD signal decrease in the brainstem and hypothalamus.•The BOLD signal decrease was mediated by changes in blood glucose and insulin,...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Academic Press
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075342/ |