Distinct Stromal Cell Factor Combinations Can Separately Control Hematopoietic Stem Cell Survival, Proliferation, and Self-Renewal

Distinct Stromal Cell Factor Combinations Can Separately Control Hematopoietic Stem Cell Survival, Proliferation, and Self-Renewal

Hematopoietic stem cells (HSCs) are identified by their ability to sustain prolonged blood cell production in vivo, although recent evidence suggests that durable self-renewal (DSR) is shared by HSC subtypes with distinct self-perpetuating differentiation programs. Net expansions of DSR-HSCs occur i...

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Bibliographic Details
Main Authors: Wohrer, Stefan, Knapp, David J.H.F., Copley, Michael R., Benz, Claudia, Kent, David G., Rowe, Keegan, Babovic, Sonja, Mader, Heidi, Oostendorp, Robert A.J., Eaves, Connie J.
Format: Online
Language:English
Published: Cell Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074342/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074342/

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