Antigen capture and archiving by lymphatic endothelial cells following vaccination or viral infection

Antigen derived from viral infections with influenza and Vesicular Stomatitis Virus (VSV) can persist after resolution of infection. Here we show that antigen can similarly persist for weeks following viral challenge and vaccination. Antigen is captured by Lymphatic Endothelial Cells (LECs), under c...

Full description

Bibliographic Details
Main Authors: Tamburini, Beth A, Burchill, Matthew A, Kedl, Ross M
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073648/