Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells

Genome-wide association studies (GWAS) and subsequent dense-genotyping of associated loci identified over a hundred single-nucleotide polymorphism (SNP) variants associated with the risk of rheumatoid arthritis (RA), type 1 diabetes (T1D), and celiac disease (CeD). Immunological and genetic studies...

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Main Authors: Hu, Xinli, Kim, Hyun, Raj, Towfique, Brennan, Patrick J., Trynka, Gosia, Teslovich, Nikola, Slowikowski, Kamil, Chen, Wei-Min, Onengut, Suna, Baecher-Allan, Clare, De Jager, Philip L., Rich, Stephen S., Stranger, Barbara E., Brenner, Michael B., Raychaudhuri, Soumya
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072514/