Integrating Diverse Datasets Improves Developmental Enhancer Prediction

Gene-regulatory enhancers have been identified using various approaches, including evolutionary conservation, regulatory protein binding, chromatin modifications, and DNA sequence motifs. To integrate these different approaches, we developed EnhancerFinder, a two-step method for distinguishing devel...

Full description

Bibliographic Details
Main Authors: Erwin, Genevieve D., Oksenberg, Nir, Truty, Rebecca M., Kostka, Dennis, Murphy, Karl K., Ahituv, Nadav, Pollard, Katherine S., Capra, John A.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072507/