Spinal SIRT1 Activation Attenuates Neuropathic Pain in Mice

Spinal SIRT1 Activation Attenuates Neuropathic Pain in Mice

Abnormal histone acetylation occurs during neuropathic pain through an epigenetic mechanism. Silent information regulator 1 (sir2 or SIRT1), a NAD-dependent deacetylase, plays complex systemic roles in a variety of processes through deacetylating acetylated histone and other specific substrates. But...

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Bibliographic Details
Main Authors: Shao, Haijun, Xue, Qingsheng, Zhang, Fujun, Luo, Yan, Zhu, Hao, Zhang, Xiaoqing, Zhang, Honghai, Ding, Wenlong, Yu, Buwei
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069177/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069177/

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