PPARβ/δ activation of CD300a controls intestinal immunity

PPARβ/δ activation of CD300a controls intestinal immunity

Macrophages are important for maintaining intestinal immune homeostasis. Here, we show that PPARβ/δ (peroxisome proliferator-activated receptor β/δ) directly regulates CD300a in macrophages that express the immunoreceptor tyrosine based-inhibitory motif (ITIM)-containing receptor. In mice lacking CD...

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Bibliographic Details
Main Authors: Tanaka, Toshiya, Tahara-Hanaoka, Satoko, Nabekura, Tsukasa, Ikeda, Kaori, Jiang, Shuying, Tsutsumi, Shuichi, Inagaki, Takeshi, Magoori, Kenta, Higurashi, Takuma, Takahashi, Hirokazu, Tachibana, Keisuke, Tsurutani, Yuya, Raza, Sana, Anai, Motonobu, Minami, Takashi, Wada, Youichiro, Yokote, Koutaro, Doi, Takefumi, Hamakubo, Takao, Auwerx, Johan, Gonzalez, Frank J., Nakajima, Atsushi, Aburatani, Hiroyuki, Naito, Makoto, Shibuya, Akira, Kodama, Tatsuhiko, Sakai, Juro
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067692/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067692/

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