TRAF2 is an NF-κB activating oncogene in epithelial cancers

Aberrant NF-κB activation is frequently observed in human cancers. Genome characterization efforts have identified genetic alterations in multiple components of the NF-κB pathway, some of which have been shown to be essential for cancer initiation and tumor maintenance. Here using patient tumors and...

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Bibliographic Details
Main Authors: Shen, Rhine R., Zhou, Alicia Y., Kim, Eejung, O’Connell, Joyce T., Hagerstrand, Daniel, Beroukhim, Rameen, Hahn, William C.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067463/