Assessing age-related gray matter decline with voxel-based morphometry depends significantly on segmentation and normalization procedures

Healthy ageing coincides with a progressive decline of brain gray matter (GM) ultimately affecting the entire brain. For a long time, manual delineation-based volumetry within predefined regions of interest (ROI) has been the gold standard for assessing such degeneration. Voxel-Based Morphometry (VB...

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Bibliographic Details
Main Authors: Callaert, Dorothée V., Ribbens, Annemie, Maes, Frederik, Swinnen, Stephan P., Wenderoth, Nicole
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066859/