The normal function of the cancer kinase Mirk/dyrk1B is to reduce reactive oxygen species

Mirk kinase is a gene upregulated and sometimes amplified in pancreatic cancers and in ovarian cancers, but expressed at very low levels in most normal diploid cells except for skeletal muscle. The muscle cell function of Mirk kinase selected for by cancer cells is unknown. It is now shown that Mirk...

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Bibliographic Details
Main Authors: Deng, Xiaobing, Mercer, Stephen E., Sun, Chi-Yu, Friedman, Eileen
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063251/