Synthetic induction of immunogenic cell death by genetic stimulation of endoplasmic reticulum stress

Cis-diamminedichloridoplatinum(II) (CDDP), commonly referred to as cisplatin, is a chemotherapeutic drug used for the treatment of a wide range of solid cancers. CDDP is a relatively poor inducer of immunogenic cell death (ICD), a cell death modality that converts dying cells into a tumor vaccine, s...

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Bibliographic Details
Main Authors: Michaud, Mickaël, Sukkurwala, Abdul Qader, Di Sano, Federica, Zitvogel, Laurence, Kepp, Oliver, Kroemer, Guido
Format: Online
Language:English
Published: Landes Bioscience 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063145/