Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions

Tumours require a vascular supply to grow and can achieve this via the expression of pro-angiogenic growth factors, including members of the vascular endothelial growth factor (VEGF) family of ligands. Since one or more of the VEGF ligand family is overexpressed in most solid cancers, there was gre...

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Bibliographic Details
Main Authors: Vasudev, Naveen S., Reynolds, Andrew R.
Format: Online
Language:English
Published: Springer Netherlands 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061466/