Insulin-Like Growth Factor 2 Silencing Restores Taxol Sensitivity in Drug Resistant Ovarian Cancer

Drug resistance is an obstacle to the effective treatment of ovarian cancer. We and others have shown that the insulin-like growth factor (IGF) signaling pathway is a novel potential target to overcome drug resistance. The purpose of this study was to validate IGF2 as a potential therapeutic target...

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Bibliographic Details
Main Authors: Brouwer-Visser, Jurriaan, Lee, Jiyeon, McCullagh, KellyAnne, Cossio, Maria J., Wang, Yanhua, Huang, Gloria S.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059749/