Overexpression of piRNA Pathway Genes in Epithelial Ovarian Cancer

The importance of the Piwi-interacting RNA (piRNA) pathway for germ cell maintenance, genome integrity, DNA methylation and retrotransposon control raises possible roles of this pathway in cancer. Indeed aberrant expression of human PIWI orthologs and Maelstrom has been observed in various cancers....

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Bibliographic Details
Main Authors: Lim, Shu Ly, Ricciardelli, Carmela, Oehler, Martin K., De Arao Tan, Izza M. D., Russell, Darryl, Grützner, Frank
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059699/