Detecting independent and recurrent copy number aberrations using interval graphs
Motivation: Somatic copy number aberrations (SCNAs) are frequent in cancer genomes, but many of these are random, passenger events. A common strategy to distinguish functional aberrations from passengers is to identify those aberrations that are recurrent across multiple samples. However, the extens...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Oxford University Press
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058951/ |