TLR9 Ligand (CpG Oligodeoxynucleotide) Induces CLL B-Cells to Differentiate into CD20+ Antibody-Secreting Cells

B-cell chronic lymphocytic leukemia (CLL) is the most frequent adult leukemia in the Western world. It is a heterogeneous disease characterized by clonal proliferation and the accumulation of CD5+ mature B lymphocytes. However, the normal counterpart from which the latter cells arise has not yet bee...

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Bibliographic Details
Main Authors: Ghamlouch, Hussein, Ouled-Haddou, Hakim, Guyart, Aude, Regnier, Aline, Trudel, Stéphanie, Claisse, Jean-François, Fuentes, Vincent, Royer, Bruno, Marolleau, Jean-Pierre, Gubler, Brigitte
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058906/