TLR9 Ligand (CpG Oligodeoxynucleotide) Induces CLL B-Cells to Differentiate into CD20+ Antibody-Secreting Cells
B-cell chronic lymphocytic leukemia (CLL) is the most frequent adult leukemia in the Western world. It is a heterogeneous disease characterized by clonal proliferation and the accumulation of CD5+ mature B lymphocytes. However, the normal counterpart from which the latter cells arise has not yet bee...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058906/ |