In Vitro Inhibition of Hepatitis C Virus by Antisense Oligonucleotides in PBMC Compared to Hepatoma Cells
Aim. To assess the efficiency of phosphorothioate antisense oligodeoxynucleotide 1 (S-ODN1) on HCV translation inhibition in PBMC compared to hepatoma cells in vitro for the first time. Materials and Methods. The study included 34 treatment naive HCV patients. IRES domain III and IV sequence variat...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058683/ |