Alpha-Bulges in G Protein-Coupled Receptors
Agonist binding is related to a series of motions in G protein-coupled receptors (GPCRs) that result in the separation of transmembrane helices III and VI at their cytosolic ends and subsequent G protein binding. A large number of smaller motions also seem to be associated with activation. Most heli...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Molecular Diversity Preservation International (MDPI)
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057707/ |