RNA-Seq Transcriptome Profiling Identifies CRISPLD2 as a Glucocorticoid Responsive Gene that Modulates Cytokine Function in Airway Smooth Muscle Cells

RNA-Seq Transcriptome Profiling Identifies CRISPLD2 as a Glucocorticoid Responsive Gene that Modulates Cytokine Function in Airway Smooth Muscle Cells

Asthma is a chronic inflammatory respiratory disease that affects over 300 million people worldwide. Glucocorticoids are a mainstay therapy for asthma because they exert anti-inflammatory effects in multiple lung tissues, including the airway smooth muscle (ASM). However, the mechanism by which gluc...

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Bibliographic Details
Main Authors: Himes, Blanca E., Jiang, Xiaofeng, Wagner, Peter, Hu, Ruoxi, Wang, Qiyu, Klanderman, Barbara, Whitaker, Reid M., Duan, Qingling, Lasky-Su, Jessica, Nikolos, Christina, Jester, William, Johnson, Martin, Panettieri, Reynold A., Tantisira, Kelan G., Weiss, Scott T., Lu, Quan
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057123/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057123/

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