Molecular Profiling and Clinical Outcome of High-Grade Serous Ovarian Cancer Presenting with Low- versus High-Volume Ascites

Molecular Profiling and Clinical Outcome of High-Grade Serous Ovarian Cancer Presenting with Low- versus High-Volume Ascites

Epithelial ovarian cancer consists of multiple histotypes differing in etiology and clinical course. The most prevalent histotype is high-grade serous ovarian cancer (HGSOC), which often presents at an advanced stage frequently accompanied with high-volume ascites. While some studies suggest that as...

Full description

Bibliographic Details
Main Authors:	Feigenberg, Tomer, Clarke, Blaise, Virtanen, Carl, Plotkin, Anna, Letarte, Michelle, Rosen, Barry, Bernardini, Marcus Q., Kollara, Alexandra, Brown, Theodore J., Murphy, K. Joan
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055662/

Similar Items

The role of KIF14 in patient-derived primary cultures of high-grade serous ovarian cancer cells
by: Thériault, Brigitte L, et al.
Published: (2014)

Targeting the Microenvironment in High Grade Serous Ovarian Cancer
by: Nkechiyere G. Nwani, et al.
Published: (2018-08-01)

Concurrent Primary Peritoneal Low-Grade Serous Carcinoma and Endometrial High-Grade Serous Carcinoma
by: Lockyer, Megan G., et al.
Published: (2015)

High Throughput Interrogation of Somatic Mutations in High Grade Serous Cancer of the Ovary
by: Matulonis, Ursula A., et al.
Published: (2011)

High-grade serous carcinoma with discordant p53 signature: report of a case with new insight regarding high-grade serous carcinogenesis
by: Yuichiro Hatano, et al.
Published: (2018-04-01)

Ascites regression following neoadjuvant chemotherapy in prediction of treatment outcome among stage IIIc to IV high-grade serous ovarian cancer
by: Xu, Xia, et al.
Published: (2016)

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary
by: Ahmed, Ahmed Ashour, et al.
Published: (2010)

No evidence for PALB2 methylation in high-grade serous ovarian cancer
by: Mikeska, Thomas, et al.
Published: (2013)

The peritoneal tumour microenvironment of high-grade serous ovarian cancer
by: Leinster, D Andrew, et al.
Published: (2012)

Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma
by: Rosie T. Jiang, et al.
Published: (2017-08-01)

Similar protein expression profiles of ovarian and endometrial high-grade serous carcinomas
by: Hiramatsu, Kosuke, et al.
Published: (2016)

MRI for differentiating ovarian endometrioid adenocarcinoma from high-grade serous adenocarcinoma
by: Li, Hai Ming, et al.
Published: (2015)

Dysregulation of X Chromosome Inactivation in High Grade Ovarian Serous Adenocarcinoma
by: Kang, Jun, et al.
Published: (2015)

Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas
by: Tone, Alicia A, et al.
Published: (2014)

Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous Carcinoma
by: Jena, Saubhagya Kumar, et al.
Published: (2015)

A survival analysis comparing women with ovarian low-grade serous carcinoma to those with high-grade histology
by: Chen, Ming, et al.
Published: (2014)

Soluble osteopontin concentrations in serum and ascites of women with advanced serous ovarian cancer
by: Černe, Katarina, et al.
Published: (2012)

High levels of pretreatment CA125 are associated to improved survival in high grade serous ovarian carcinoma
by: Morales-Vásquez, Flavia, et al.
Published: (2016)

CT features of low grade serous carcinoma of the ovary
by: Pannu, Harpreet K.
Published: (2015)

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer
by: Lawrenson, Kate, et al.
Published: (2015)

Endometrioid Adenocarcinoma with High-Grade Transformation with Serous and Choriocarcinomatous Differentiation - A Case Report
by: Wakahashi, Senn, et al.
Published: (2011)

Molecular Clustering Based on ERα and EIG121 Predicts Survival in High-Grade Serous Carcinoma of the Ovary/Peritoneum
by: Schlumbrecht, Matthew P., et al.
Published: (2010)

Amplification of The ch19p13.2 NACC1 Locus in Ovarian High-grade Serous Carcinoma
by: Shih, Ie-Ming, et al.
Published: (2011)

Deregulation of MYCN, LIN28B and LET7 in a Molecular Subtype of Aggressive High-Grade Serous Ovarian Cancers
by: Helland, Åslaug, et al.
Published: (2011)

DNA Damage Response is Prominent in Ovarian High-Grade Serous Carcinomas, Especially Those with Rsf-1 (HBXAP) Overexpression
by: Kshirsagar, Malti, et al.
Published: (2012)

Integrated Analyses of microRNAs Demonstrate Their Widespread Influence on Gene Expression in High-Grade Serous Ovarian Carcinoma
by: Creighton, Chad J., et al.
Published: (2012)

Pancreatic Metastasis of High-Grade Papillary Serous Ovarian Carcinoma Mimicking Primary Pancreas Cancer: A Case Report
by: Gunay, Yusuf, et al.
Published: (2012)

Nadir CA-125 level as prognosis indicator of high-grade serous ovarian cancer
by: Xu, Xia, et al.
Published: (2013)

The Molecular Fingerprint of High Grade Serous Ovarian Cancer Reflects Its Fallopian Tube Origin
by: Kessler, Mirjana, et al.
Published: (2013)

Modeling High-Grade Serous Carcinoma: How Converging Insights into Pathogenesis and Genetics are Driving Better Experimental Platforms
by: Jones, Paul Michael, et al.
Published: (2013)

Clinical Relevance of Gain-Of-Function Mutations of p53 in High-Grade Serous Ovarian Carcinoma
by: Kang, Hyo Jeong, et al.
Published: (2013)

Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling
by: Bashashati, Ali, et al.
Published: (2013)

High-Grade Serous Tumor Arising from Fallopian Tube in a BRCA Mutation Carrier after Prophylactic Oophorectomy
by: Lorusso, Domenica, et al.
Published: (2013)

Predictive Modeling Using a Somatic Mutational Profile in Ovarian High Grade Serous Carcinoma
by: Sohn, Insuk, et al.
Published: (2013)

NotI Microarrays: Novel Epigenetic Markers for Early Detection and Prognosis of High Grade Serous Ovarian Cancer
by: Kashuba, Vladimir, et al.
Published: (2012)

Markers of T Cell Infiltration and Function Associate with Favorable Outcome in Vascularized High-Grade Serous Ovarian Carcinoma
by: Townsend, Katelin N., et al.
Published: (2013)

Metastatic ovarian papillary cystadenocarcinoma to the small intestine serous surface: report of a case of high-grade histopathologic malignancy
by: Khaki, Fariba, et al.
Published: (2014)

Reversing Platinum Resistance in High-Grade Serous Ovarian Carcinoma: Targeting BRCA and the Homologous Recombination System
by: Wiedemeyer, W. Ruprecht, et al.
Published: (2014)

Modeling Platinum Sensitive and Resistant High-Grade Serous Ovarian Cancer: Development and Applications of Experimental Systems
by: Cunnea, Paula, et al.
Published: (2014)

A New Spontaneously Transformed Syngeneic Model of High-Grade Serous Ovarian Cancer with a Tumor-Initiating Cell Population
by: McCloskey, Curtis W., et al.
Published: (2014)