Dual targeting of heat shock proteins 90 and 70 promotes cell death and enhances the anticancer effect of chemotherapeutic agents in bladder cancer

Dual targeting of heat shock proteins 90 and 70 promotes cell death and enhances the anticancer effect of chemotherapeutic agents in bladder cancer

Heat shock proteins (HSPs), which are molecular chaperones that stabilize numerous vital proteins, may be attractive targets for cancer therapy. The aim of the present study was to investigate the possible anticancer effect of single or dual targeting of HSP90 and HSP70 and the combination treatment...

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Main Authors: MA, LIANG, SATO, FUMINORI, SATO, RYUTA, MATSUBARA, TAKANORI, HIRAI, KENICHI, YAMASAKI, MUTSUSHI, SHIN, TOSHITAKA, SHIMADA, TATSUO, NOMURA, TAKEO, MORI, KENICHI, SUMINO, YASUHIRO, MIMATA, HIROMITSU
Format: Online
Language:English
Published: D.A. Spandidos 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055347/

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