Sustained-input switches for transcription factors and microRNAs are central building blocks of eukaryotic gene circuits

WaRSwap is a randomization algorithm that for the first time provides a practical network motif discovery method for large multi-layer networks, for example those that include transcription factors, microRNAs, and non-regulatory protein coding genes. The algorithm is applicable to systems with tens...

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Bibliographic Details
Main Authors: Megraw, Molly, Mukherjee, Sayan, Ohler, Uwe
Format: Online
Language:English
Published: BioMed Central 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054853/