Implications of Differential Age Distribution of Disease-Associated Meningococcal Lineages for Vaccine Development

Implications of Differential Age Distribution of Disease-Associated Meningococcal Lineages for Vaccine Development

New vaccines targeting meningococci expressing serogroup B polysaccharide have been developed, with some being licensed in Europe. Coverage depends on the distribution of disease-associated genotypes, which may vary by age. It is well established that a small number of hyperinvasive lineages account...

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Main Authors: Brehony, Carina, Trotter, Caroline L., Ramsay, Mary E., Chandra, Manosree, Jolley, Keith A., van der Ende, Arie, Carion, Françoise, Berthelsen, Lene, Hoffmann, Steen, Harðardóttir, Hjördís, Vazquez, Julio A., Murphy, Karen, Toropainen, Maija, Caniça, Manuela, Ferreira, Eugenia, Diggle, Mathew, Edwards, Giles F., Taha, Muhamed-Kheir, Stefanelli, Paola, Kriz, Paula, Gray, Steve J., Fox, Andrew J., Jacobsson, Susanne, Claus, Heike, Vogel, Ulrich, Tzanakaki, Georgina, Heuberger, Sigrid, Caugant, Dominique A., Frosch, Matthias, Maiden, Martin C. J.
Format: Online
Language:English
Published: American Society for Microbiology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054250/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054250/

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