Estrogen improves the proliferation and differentiation of hBMSCs derived from postmenopausal osteoporosis through notch signaling pathway

Estrogen deficiency is the main reason of bone loss, leading to postmenopausal osteoporosis, and estrogen replacement therapy (ERT) has been demonstrated to protect bone loss efficiently. Notch signaling controls proliferation and differentiation of bone marrow-derived mesenchymal stem cells (BMSCs...

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Bibliographic Details
Main Authors: Fan, Jin-Zhu, Yang, Liu, Meng, Guo-Lin, Lin, Yan-shui, Wei, Bo-Yuan, Fan, Jing, Hu, Hui-Min, Liu, Yan-Wu, Chen, Shi, Zhang, Jin-Kang, He, Qi-Zhen, Luo, Zhuo-Jing, Liu, Jian
Format: Online
Language:English
Published: Springer US 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053611/