Enzymatic Sialylation of IgA1 O-Glycans: Implications for Studies of IgA Nephropathy

Patients with IgA nephropathy (IgAN) have elevated circulating levels of IgA1 with some O-glycans consisting of galactose (Gal)-deficient N-acetylgalactosamine (GalNAc) with or without N-acetylneuraminic acid (NeuAc). We have analyzed O-glycosylation heterogeneity of naturally asialo-IgA1 (Ale) myel...

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Bibliographic Details
Main Authors: Takahashi, Kazuo, Raska, Milan, Stuchlova Horynova, Milada, Hall, Stacy D., Poulsen, Knud, Kilian, Mogens, Hiki, Yoshiyuki, Yuzawa, Yukio, Moldoveanu, Zina, Julian, Bruce A., Renfrow, Matthew B., Novak, Jan
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053367/