CARM1 and BAF155: an example of how chromatin remodeling factors can be relocalized and contribute to cancer

In a recent article, Wang and colleagues reported the discovery of a mechanism by which CARM1 regulates the genomic localization of BAF155 (a SWI/SNF subunit involved in chromatin remodeling) through post-translational methylation at R1064 arginine residues. This modification leads to the relocaliza...

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Bibliographic Details
Main Authors: Stefansson, Olafur A, Esteller, Manel
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053224/