PMA Induces Vaccine Adjuvant Activity by the Modulation of TLR Signaling Pathway

Toll-like receptor (TLR) ligands are being developed for use as vaccine adjuvants and as immunomodulators because of their ability to stimulate innate and adaptive immune responses. Flagellin, a TLR5 ligand, was reported to show potent mucosal vaccine adjuvant activity. To identify ligands that pote...

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Bibliographic Details
Main Authors: Oh, Dool-Ri, Kang, Hu Won, Kim, Jong-Ro, Kim, Sunoh, Park, In-Kyu, Rhee, Joon Haeng, Oh, Won Keun, Kim, Young Ran
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052173/