Gremlin Activates the Smad Pathway Linked to Epithelial Mesenchymal Transdifferentiation in Cultured Tubular Epithelial Cells

Gremlin Activates the Smad Pathway Linked to Epithelial Mesenchymal Transdifferentiation in Cultured Tubular Epithelial Cells

Gremlin is a developmental gene upregulated in human chronic kidney disease and in renal cells in response to transforming growth factor-β (TGF-β). Epithelial mesenchymal transition (EMT) is one process involved in renal fibrosis. In tubular epithelial cells we have recently described that Gremlin i...

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Bibliographic Details
Main Authors: Rodrigues-Diez, Raquel, Rodrigues-Diez, Raúl R., Lavoz, Carolina, Carvajal, Gisselle, Droguett, Alejandra, Garcia-Redondo, Ana B., Rodriguez, Isabel, Ortiz, Alberto, Egido, Jesús, Mezzano, Sergio, Ruiz-Ortega, Marta
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052161/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052161/

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