Generation and Characterisation of a Canine EGFP-HMGA2 Prostate Cancer In Vitro Model

The architectural transcription factor HMGA2 is abundantly expressed during embryonic development. In several malignant neoplasias including prostate cancer, high re-expression of HMGA2 is correlated with malignancy and poor prognosis. The let-7 miRNA family is described to regulate HMGA2 negatively...

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Bibliographic Details
Main Authors: Willenbrock, Saskia, Wagner, Siegfried, Reimann-Berg, Nicola, Moulay, Mohammed, Hewicker-Trautwein, Marion, Nolte, Ingo, Escobar, Hugo Murua
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051699/