Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFβ signaling

Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFβ signaling

•SND1 augments AT1R receptor level by posttranscriptional regulation.•SND1 activates TGFβ signaling which promotes the epithelial–mesenchymal transition.•Migration and invasion by human hepatocellular carcinoma (HCC) cells are augmented by SND1.•A correlation is observed between SND1 and AT1R expres...

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Bibliographic Details
Main Authors: Santhekadur, Prasanna K., Akiel, Maaged, Emdad, Luni, Gredler, Rachel, Srivastava, Jyoti, Rajasekaran, Devaraja, Robertson, Chadia L., Mukhopadhyay, Nitai D., Fisher, Paul B., Sarkar, Devanand
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050181/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050181/

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