Adenosquamous carcinoma of the conjunctiva: A case report

Adenosquamous carcinoma of the conjunctiva: A case report

Adenosquamous carcinoma (ASC) is a rare form of malignancy which consists of two types of cell, including squamous cells and glandular-like cells. The current report presents the first known case of ASC in the conjunctiva and analyzes the histological findings. A 76-year-old female presented with ri...

Full description

Bibliographic Details
Main Authors: KASE, SATORU, YOSHIKAWA, HIROSHI, NAKAJIMA, YUTAKA, NODA, MIKA, ISHIDA, SUSUMU
Format: Online
Language:English
Published: D.A. Spandidos 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049748/
id pubmed-4049748
recordtype oai_dc
spelling pubmed-40497482014-06-13 Adenosquamous carcinoma of the conjunctiva: A case report KASE, SATORU YOSHIKAWA, HIROSHI NAKAJIMA, YUTAKA NODA, MIKA ISHIDA, SUSUMU Articles Adenosquamous carcinoma (ASC) is a rare form of malignancy which consists of two types of cell, including squamous cells and glandular-like cells. The current report presents the first known case of ASC in the conjunctiva and analyzes the histological findings. A 76-year-old female presented with right eyelid swelling in 2001. A right conjunctival tumor was noted and a biopsy was performed. Histologically, the tumor was diagnosed as a squamous cell carcinoma. The patient underwent radiotherapy, but the tumor rapidly relapsed. Subsequently, the patient underwent orbital exenteration. Histologically, the conjunctival tissues had been replaced with invasive tumor cells. A number of tumor cells demonstrated squamous differentiation with a keratinizing tendency, while other tumor cells exhibited mucin-producing activity with glandular formation. The conjunctival tumor was diagnosed as an ASC. At the time of writing, the patient is well without local recurrence or distant metastases. ASC typically exhibits aggressive biological behavior, and is associated with worse prognosis than conventional adenocarcinoma. Therefore, complete surgical excision is considered a key treatment for ASC of the conjunctiva. D.A. Spandidos 2014-06 2014-03-28 /pmc/articles/PMC4049748/ /pubmed/24932264 http://dx.doi.org/10.3892/ol.2014.2008 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author KASE, SATORU
YOSHIKAWA, HIROSHI
NAKAJIMA, YUTAKA
NODA, MIKA
ISHIDA, SUSUMU
spellingShingle KASE, SATORU
YOSHIKAWA, HIROSHI
NAKAJIMA, YUTAKA
NODA, MIKA
ISHIDA, SUSUMU
Adenosquamous carcinoma of the conjunctiva: A case report
author_facet KASE, SATORU
YOSHIKAWA, HIROSHI
NAKAJIMA, YUTAKA
NODA, MIKA
ISHIDA, SUSUMU
author_sort KASE, SATORU
title Adenosquamous carcinoma of the conjunctiva: A case report
title_short Adenosquamous carcinoma of the conjunctiva: A case report
title_full Adenosquamous carcinoma of the conjunctiva: A case report
title_fullStr Adenosquamous carcinoma of the conjunctiva: A case report
title_full_unstemmed Adenosquamous carcinoma of the conjunctiva: A case report
title_sort adenosquamous carcinoma of the conjunctiva: a case report
description Adenosquamous carcinoma (ASC) is a rare form of malignancy which consists of two types of cell, including squamous cells and glandular-like cells. The current report presents the first known case of ASC in the conjunctiva and analyzes the histological findings. A 76-year-old female presented with right eyelid swelling in 2001. A right conjunctival tumor was noted and a biopsy was performed. Histologically, the tumor was diagnosed as a squamous cell carcinoma. The patient underwent radiotherapy, but the tumor rapidly relapsed. Subsequently, the patient underwent orbital exenteration. Histologically, the conjunctival tissues had been replaced with invasive tumor cells. A number of tumor cells demonstrated squamous differentiation with a keratinizing tendency, while other tumor cells exhibited mucin-producing activity with glandular formation. The conjunctival tumor was diagnosed as an ASC. At the time of writing, the patient is well without local recurrence or distant metastases. ASC typically exhibits aggressive biological behavior, and is associated with worse prognosis than conventional adenocarcinoma. Therefore, complete surgical excision is considered a key treatment for ASC of the conjunctiva.
publisher D.A. Spandidos
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049748/
_version_ 1612098347573706752

Similar Items