Omega-3 Free Fatty Acids Suppress Macrophage Inflammasome Activation by Inhibiting NF-κB Activation and Enhancing Autophagy

Omega-3 Free Fatty Acids Suppress Macrophage Inflammasome Activation by Inhibiting NF-κB Activation and Enhancing Autophagy

The omega-3 (ω3) fatty acid docosahexaenoic acid (DHA) can suppress inflammation, specifically IL-1β production through poorly understood molecular mechanisms. Here, we show that DHA reduces macrophage IL-1β production by limiting inflammasome activation. Exposure to DHA reduced IL-1β production by...

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Bibliographic Details
Main Authors: Williams-Bey, Yolanda, Boularan, Cedric, Vural, Ali, Huang, Ning-Na, Hwang, Il-Young, Shan-Shi, Chong, Kehrl, John H.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049592/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049592/

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