Altered expression of Alzheimer's disease-related genes in the cerebellum of autistic patients: a model for disrupted brain connectome and therapy

Autism and Alzheimer's disease (AD) are, respectively, neurodevelopmental and degenerative diseases with an increasing epidemiological burden. The AD-associated amyloid-β precursor protein-α has been shown to be elevated in severe autism, leading to the ‘anabolic hypothesis' of its etiolog...

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Bibliographic Details
Main Authors: Zeidán-Chuliá, F, de Oliveira, B-HN, Salmina, A B, Casanova, M F, Gelain, D P, Noda, M, Verkhratsky, A, Moreira, J CF
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047885/