Elf3 drives β-catenin transactivation and associates with poor prognosis in colorectal cancer

Elf3 drives β-catenin transactivation and associates with poor prognosis in colorectal cancer

Aberrant regulation of the Wnt/β-catenin pathway plays important roles in colorectal carcinogenesis, with over 90% of cases of sporadic colon cancer featuring β-catenin accumulation. While ubiquitination-mediated degradation is widely accepted as a major route for β-catenin protein turnover, little...

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Bibliographic Details
Main Authors:	Wang, J-L, Chen, Z-F, Chen, H-M, Wang, M-Y, Kong, X, Wang, Y-C, Sun, T-T, Hong, J, Zou, W, Xu, J, Fang, J-Y
Format:	Online
Language:	English
Published:	Nature Publishing Group 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047871/

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