A Loss of Function Analysis of Host Factors Influencing Vaccinia virus Replication by RNA Interference

A Loss of Function Analysis of Host Factors Influencing Vaccinia virus Replication by RNA Interference

Vaccinia virus (VACV) is a large, cytoplasmic, double-stranded DNA virus that requires complex interactions with host proteins in order to replicate. To explore these interactions a functional high throughput small interfering RNA (siRNA) screen targeting 6719 druggable cellular genes was undertake...

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Bibliographic Details
Main Authors: Beard, Philippa M., Griffiths, Samantha J., Gonzalez, Orland, Haga, Ismar R., Pechenick Jowers, Tali, Reynolds, Danielle K., Wildenhain, Jan, Tekotte, Hille, Auer, Manfred, Tyers, Mike, Ghazal, Peter, Zimmer, Ralf, Haas, Jürgen
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047015/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047015/

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