Effects of Angiopoietin-1 on Hemorrhagic Transformation and Cerebral Edema after Tissue Plasminogen Activator Treatment for Ischemic Stroke in Rats

Effects of Angiopoietin-1 on Hemorrhagic Transformation and Cerebral Edema after Tissue Plasminogen Activator Treatment for Ischemic Stroke in Rats

An angiogenesis factor, angiopoietin-1 (Ang1), is associated with the blood-brain barrier (BBB) disruption after focal cerebral ischemia. However, whether hemorrhagic transformation and cerebral edema after tissue plasminogen activator (tPA) treatment are related to the decrease in Ang1 expression i...

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Bibliographic Details
Main Authors: Kawamura, Kunio, Takahashi, Tetsuya, Kanazawa, Masato, Igarashi, Hironaka, Nakada, Tsutomu, Nishizawa, Masatoyo, Shimohata, Takayoshi
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045756/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045756/

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