Synergistic Radioprotection by Gamma-Tocotrienol and Pentoxifylline: Role of cAMP Signaling

Purpose. This study was designed to determine the efficacy and mechanisms of radioprotection by the combination of gamma-tocotrienol (GT3) and pentoxifylline (PTX) against acute radiation injury. Materials and Methods. Post-irradiation survival was monitored to determine the most efficacious dose a...

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Bibliographic Details
Main Authors: Kulkarni, Shilpa, Chakraborty, Kushal, Kumar, K. Sree, Kao, Tzu-Cheg, Hauer-Jensen, Martin, Ghosh, Sanchita P.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045513/