Integrin α6A splice variant regulates proliferation and the Wnt/β-catenin pathway in human colorectal cancer cells
Integrin α6Aβ4 is up-regulated in colorectal cancers. Knockdown of α6A in adenocarcinoma cell lines revealed a sustained reduction of cell growth both in cellulo and in xenografts as well as a repression of a number of Wnt/β-catenin pathway end points.
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Oxford University Press
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043246/ |