RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells

The RNA polymerase II largest subunit (Rpb1) contains a unique C-terminal domain (CTD) that plays multiple roles during transcription. The CTD is composed of consensus Y1S2P3T4S5P6S7 repeats, in which Ser, Thr and Tyr residues can all be phosphorylated. Here we report analysis of CTD Tyr1 using gene...

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Bibliographic Details
Main Authors: Hsin, Jing-Ping, Li, Wencheng, Hoque, Mainul, Tian, Bin, Manley, James L
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042873/