Preclinical Therapeutic Potential of a Nitrosylating Agent in the Treatment of Ovarian Cancer

This study examines the role of s-nitrosylation in the growth of ovarian cancer using cell culture based and in vivo approaches. Using the nitrosylating agent, S-nitrosoglutathione (GSNO), a physiological nitric oxide molecule, we show that GSNO treatment inhibited proliferation of chemoresponsive a...

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Bibliographic Details
Main Authors: Giri, Shailendra, Rattan, Ramandeep, Deshpande, Mandar, Maguire, Jacie L., Johnson, Zachary, Graham, Rondell P., Shridhar, Viji
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041717/