Targeting vertebrate intron-encoded box C/D 2′-O-methylation guide RNAs into the Cajal body

Post-transcriptional pseudouridylation and 2′-O-methylation of splicesomal small nuclear ribonucleic acids (snRNAs) is mediated by box H/ACA and box C/D small Cajal body (CB)-specific ribonucleoproteins (scaRNPs), respectively. The WD-repeat protein 79 (WDR79) has been proposed to interact with both...

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Bibliographic Details
Main Authors: Marnef, Aline, Richard, Patrica, Pinzón, Natalia, Kiss, Tamás
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041459/