Targeted therapy in melanoma – the role of BRAF, RAS and KIT mutations

Melanoma today is considered as a spectrum of melanocytic malignancies characterised by clinical and molecular features, including targetable mutations in several kinases such as BRAF or c-KIT. The successful development of therapies targeting these mutations has resulted in new specific treatment o...

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Bibliographic Details
Main Authors: Goldinger, Simone M., Murer, Carla, Stieger, Pascale, Dummer, Reinhard
Format: Online
Language:English
Published: Elsevier 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041182/