Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN

Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN

Celecoxib, a COX-2 inhibitor and non-steroidal anti-inflammatory drug, can prevent several types of cancer, including hepatocellular carcinoma (HCC). Here we show that celecoxib suppressed the self-renewal and drug-pumping functions in HCC cells. Besides, celecoxib depleted CD44 + /CD133 + hepatic c...

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Bibliographic Details
Main Authors: Chu, Tian-Huei, Chan, Hoi-Hung, Kuo, Hsiao-Mei, Liu, Li-Fen, Hu, Tsung-Hui, Sun, Cheuk-Kwan, Kung, Mei-Lang, Lin, Shih-Wei, Wang, E-Ming, Ma, Yi-Ling, Cheng, Kwan-Hung, Lai, Kwok Hung, Wen, Zhi-Hong, Hsu, Ping-I, Tai, Ming-Hong
Format: Online
Language:English
Published: Impact Journals LLC 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039225/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039225/

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