Optical Topography to measure variations in Regional Cerebral Oxygenation in an Infant supported on veno-arterial Extra-Corporeal Membrane Oxygenation

Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for patients with cardio-respiratory failure which exposes the patient to the risk for intracranial injury. We used a 12-channel optical topography system to monitor cerebral oxygenation in a venoarterial (VA) ECMO patient during alterat...

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Main Authors:	Papademetriou, Maria D., Tachtsidis, Ilias, Banaji, Murad, Elliott, Martin J., Hoskote, Aparna, Elwell, Clare E.
Format:	Online
Language:	English
Published:	Springer 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038014/

id	pubmed-4038014
recordtype	oai_dc
spelling	pubmed-40380142014-06-02 Optical Topography to measure variations in Regional Cerebral Oxygenation in an Infant supported on veno-arterial Extra-Corporeal Membrane Oxygenation Papademetriou, Maria D. Tachtsidis, Ilias Banaji, Murad Elliott, Martin J. Hoskote, Aparna Elwell, Clare E. Article Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for patients with cardio-respiratory failure which exposes the patient to the risk for intracranial injury. We used a 12-channel optical topography system to monitor cerebral oxygenation in a venoarterial (VA) ECMO patient during alterations in the ECMO flows. Changes in oxy-(HbO2), deoxy-(HHb) and total-(HbT) haemoglobin concentrations were measured simultaneously with systemic and ECMO circuit parameters. Decreasing the flows resulted in a decrease in venous (SvO2) and arterial (SpO2) saturations. These were reflected in the haemoglobin data by a significant increase in HHb of varying magnitude across the 12 channels and moderate changes in HbO2 suggestive of cerebral arterial dilation to compensate for the lack of oxygen delivery. In the patient studied here ECMO flows appear to present a significant haemodynamic challenge to cerebral circulation. Springer 2012 /pmc/articles/PMC4038014/ /pubmed/22259084 http://dx.doi.org/10.1007/978-1-4614-1566-4_11 Text en
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Papademetriou, Maria D. Tachtsidis, Ilias Banaji, Murad Elliott, Martin J. Hoskote, Aparna Elwell, Clare E.
spellingShingle	Papademetriou, Maria D. Tachtsidis, Ilias Banaji, Murad Elliott, Martin J. Hoskote, Aparna Elwell, Clare E. Optical Topography to measure variations in Regional Cerebral Oxygenation in an Infant supported on veno-arterial Extra-Corporeal Membrane Oxygenation
author_facet	Papademetriou, Maria D. Tachtsidis, Ilias Banaji, Murad Elliott, Martin J. Hoskote, Aparna Elwell, Clare E.
author_sort	Papademetriou, Maria D.
title	Optical Topography to measure variations in Regional Cerebral Oxygenation in an Infant supported on veno-arterial Extra-Corporeal Membrane Oxygenation
title_short	Optical Topography to measure variations in Regional Cerebral Oxygenation in an Infant supported on veno-arterial Extra-Corporeal Membrane Oxygenation
title_full	Optical Topography to measure variations in Regional Cerebral Oxygenation in an Infant supported on veno-arterial Extra-Corporeal Membrane Oxygenation
title_fullStr	Optical Topography to measure variations in Regional Cerebral Oxygenation in an Infant supported on veno-arterial Extra-Corporeal Membrane Oxygenation
title_full_unstemmed	Optical Topography to measure variations in Regional Cerebral Oxygenation in an Infant supported on veno-arterial Extra-Corporeal Membrane Oxygenation
title_sort	optical topography to measure variations in regional cerebral oxygenation in an infant supported on veno-arterial extra-corporeal membrane oxygenation
description	Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for patients with cardio-respiratory failure which exposes the patient to the risk for intracranial injury. We used a 12-channel optical topography system to monitor cerebral oxygenation in a venoarterial (VA) ECMO patient during alterations in the ECMO flows. Changes in oxy-(HbO2), deoxy-(HHb) and total-(HbT) haemoglobin concentrations were measured simultaneously with systemic and ECMO circuit parameters. Decreasing the flows resulted in a decrease in venous (SvO2) and arterial (SpO2) saturations. These were reflected in the haemoglobin data by a significant increase in HHb of varying magnitude across the 12 channels and moderate changes in HbO2 suggestive of cerebral arterial dilation to compensate for the lack of oxygen delivery. In the patient studied here ECMO flows appear to present a significant haemodynamic challenge to cerebral circulation.
publisher	Springer
publishDate	2012
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038014/
_version_	1612094445757399040

Optical Topography to measure variations in Regional Cerebral Oxygenation in an Infant supported on veno-arterial Extra-Corporeal Membrane Oxygenation

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