The spatial organization of non-homologous end joining: From bridging to end joining
•Structural analyses of NHEJ suggest mechanisms of DNA double-strand break repair.•Complexes of Artemis with LigIV and DNA-PK define spatiotemporal relationships.•Disease-causing mutations in Artemis, LigIV and XLF are explained by 3D structure.
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037875/ |