Structural changes in the temporal lobe and piriform cortex in frontal lobe epilepsy

•Voxelwise analysis of structural images is performed in a group of patients with FLE.•Structural abnormalities are found in piriform cortex and adjacent structures including amygdala.•These common areas of structural abnormality are seen independently of the side of seizure focus lateralisation.•Th...

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Main Authors: Centeno, M., Vollmar, C., Stretton, J., Symms, M.R., Thompson, P.J., Richardson, M.P., O’Muircheartaigh, J., Duncan, J.S., Koepp, M.J.
Format: Online
Language:English
Published: Elsevier Science Publishers 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037873/
id pubmed-4037873
recordtype oai_dc
spelling pubmed-40378732014-07-01 Structural changes in the temporal lobe and piriform cortex in frontal lobe epilepsy Centeno, M. Vollmar, C. Stretton, J. Symms, M.R. Thompson, P.J. Richardson, M.P. O’Muircheartaigh, J. Duncan, J.S. Koepp, M.J. Short Communication •Voxelwise analysis of structural images is performed in a group of patients with FLE.•Structural abnormalities are found in piriform cortex and adjacent structures including amygdala.•These common areas of structural abnormality are seen independently of the side of seizure focus lateralisation.•This is concordant with previous findings in functional imaging analysis of patients with focal epilepsy. Elsevier Science Publishers 2014-07 /pmc/articles/PMC4037873/ /pubmed/24726451 http://dx.doi.org/10.1016/j.eplepsyres.2014.03.001 Text en © 2014 The Authors http://creativecommons.org/licenses/by/3.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Centeno, M.
Vollmar, C.
Stretton, J.
Symms, M.R.
Thompson, P.J.
Richardson, M.P.
O’Muircheartaigh, J.
Duncan, J.S.
Koepp, M.J.
spellingShingle Centeno, M.
Vollmar, C.
Stretton, J.
Symms, M.R.
Thompson, P.J.
Richardson, M.P.
O’Muircheartaigh, J.
Duncan, J.S.
Koepp, M.J.
Structural changes in the temporal lobe and piriform cortex in frontal lobe epilepsy
author_facet Centeno, M.
Vollmar, C.
Stretton, J.
Symms, M.R.
Thompson, P.J.
Richardson, M.P.
O’Muircheartaigh, J.
Duncan, J.S.
Koepp, M.J.
author_sort Centeno, M.
title Structural changes in the temporal lobe and piriform cortex in frontal lobe epilepsy
title_short Structural changes in the temporal lobe and piriform cortex in frontal lobe epilepsy
title_full Structural changes in the temporal lobe and piriform cortex in frontal lobe epilepsy
title_fullStr Structural changes in the temporal lobe and piriform cortex in frontal lobe epilepsy
title_full_unstemmed Structural changes in the temporal lobe and piriform cortex in frontal lobe epilepsy
title_sort structural changes in the temporal lobe and piriform cortex in frontal lobe epilepsy
description •Voxelwise analysis of structural images is performed in a group of patients with FLE.•Structural abnormalities are found in piriform cortex and adjacent structures including amygdala.•These common areas of structural abnormality are seen independently of the side of seizure focus lateralisation.•This is concordant with previous findings in functional imaging analysis of patients with focal epilepsy.
publisher Elsevier Science Publishers
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037873/
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